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Transplantation Current Barriers And Prospective

Transplantation Current Barriers And Prospective

Transplantation Current Barriers And Prospective

  • Editor: Dr. Ahmed AKL
  • ISBN: 978-1-63278-032-4
  • DOI: 10.4172/978-1-63278-032-4-033
  • No of Pages: 105
  • Publisher: OMICS International
  • Published On: December 2015 , Fri 18
  • Chapter 1      
    Organ Transplantation – Historical Background
    Authors: Sir Roy Calne

    In the past 50 years organ transplantation has been established as an extremely important branch of therapeutic medicine, starting from nothing in the 1950s to the achievement.

  • Chapter 2      
    Computer Based Decision Supporting Tools in Transplantation
    Authors: Ahmed AKL, Mohamed A Ghoneim

    Transplantation informatics is a complex information based field that uses multichannel health information technology in order to improve patient health care.

  • Chapter 3      
    Induction Therapy
    Authors: Ahmed Mansour Abdel Rahman, Mohamed Adel Bakr

    Induction immunosuppression is not a compulsory stage of immunosuppressive treatment in renal transplant recipients; however, it is often considered essential to improve .

  • Chapter 4      
    Pediatric Kidney Transplantation Barriers Challenges and Outcome
    Authors: Mohammed EI Saftwy, ehab W Wafa

    Renal transplantation is the best treatment for ESKD in pediatric as better patient survival, better quality of life (Dialysis is more disruptive to family lifestyle.

  • Chapter 5      
    Pancreas Transplantation
    Authors: Diego Cantarovich

    The goal of pancreas transplantation is to induce long-lasting complete insulin independence and normal glucose metabolism in type 1 diabetic patients.

  • Chapter 6      
    Antibody Mediated Rejection: HLA-Specific B-Cells Role in Kidney Transplantation
    Authors: Ahmed AKL

    Donor specific HLA antibodies have been associated with acute and chronic rejection of organ allograft [1-3]. However, this correlation is not absolute.

  • Chapter 7      
    Functional Magnetic Resonance Imaging of Kidney Transplant: Current Status and Future Prospective
    Authors: Mohamed Abou El Ghar

    Kidney transplantation is one of therapeutic choice for patients with End-Stage Renal Disease (ESRD).

  • Chapter 8      
    Pathology of Renal Allograft Rejection: The Banff Classification System: Scoring and Pitfalls
    Authors: Mona Abdelrahim

    Immunohistochemistry for cell phenotype, viruses when required. Immunohistochemistry for C4d on paraffin if immunofluorecence was unavailable.

  • Chapter 9      
    Vaccinations of Kidney Transplants: Updates for Optimal Protection
    Authors: Essam Elsawy

    Vaccination of immuno-compromised patients is important because impaired host defenses.

  • Chapter 10      
    Viral Infections Post Transplantation
    Authors: Mohamed Hamed Abbas, Ahmed Abdelfattah Denewar

    Hepatitis C Virus (HCV) is its most leading cause of hepatic disease post renal transplantation.

  • Chapter 11      
    Impact of Recurrent Glomerular Kidney Disease Following Kidney Transplantation
    Authors: Zahab MA, Mashaly ME

    Recurrent glomerulonephritis following kidney transplantation affects between 10% and 20% of patients, and accounts for up to 8% of graft failures at 10 years Post transplant.

  • Chapter 12      
    Post Renal Transplant Malignancy
    Authors: Nabil El Serwy, Mohamed Ashraf Foda

    Kidney transplantation is generally accepted as the best treatment for patients with End Stage Renal Disease (ESRD) requiring renal replacement therapy which improves both the quality of life and life span of patients.

  • Chapter 13      
    Hematological Abnormalities Post Renal Transplantation
    Authors: Rasha kamal Abouelenein, Ayman F Refaie

    Renal transplantation is considered the surgical procedure used in renal replacement therapy.

  • Dr. Ahmed AKL

    Post-doctorate, Urology and Nephrology Center, Mansoura, Egypt

    I was graduated from my home city Mansoura University, Faculty of Medicine 1993 with grade of honor. I was lucky to start my residency at Nephrology at Urology & Nephrology center, Mansoura, Egypt. After achieving Master degree in general medicine and nephrology I was granted a nephrology fellowship in transplantation in the same center. Then I received a fellowship grant from the international society of nephrology (ISN) to have training in transplantation immunology with Professor Kathryn wood, one of the greatest mentors in transplantation science research, at Transplantation Research Immunology Group, Nuffield Department of Surgery, Oxford University, United Kingdom. My focus was on the investigation of the cellular mechanisms of graft tolerance. During my training, I received Distinguished Fellow’s Award recognition for my work from the ISN, plus many accepted publication and Chapter in one of the prestigious Textbooks in Inflammation. Once I finished my doctoral degree in Egypt, I continued my transplantation clinical practice, during that period I have focused my research in artificial intelligence and multivariate models to predict long-term graft survival. After two years of clinical practice I moved to France to start post-doctoral fellowship in Transplantation science for two years with Prof. Jean-Paul Soulillou and Dr. Sophie Brouard, Nantes University, France and the division of Nephrology, Northwestern University, USA. My knowledge and orientation was shifted from T cells mechanisms of rejection and tolerance to B cells mediated rejections. Beside that I have participated in many clinically applicable biostatistical models and several clinical publications in Transplantation and Cancer. Transplantation science is my passionate, surfing between the barriers & risks and searching for solutions with new modifications of our approaches to deliver the best aid to those humans unluckily been found to have one of their organs stopped.

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