Gastroenteritis or infectious diarrhea, generally caused by viral or bacterial or parasitic infections is responsible for morbidity and mortality, especially in children.
Multidrug Resistant (MDR) organisms are predominantly bacteria, that are resistant to one or more classes of antimicrobial agents.
The drug-resistant bacteria are currently considered as a major public health problem. The emergence of multiple resistances among major pathogenic microbes has grown alarmingly over the past few years.
Antibiotic-resistant microorganisms existed even before the clinical use of antibiotics was started. However, the real threat of the problem of drug-resistance.
Bacteria existed on this earth even before antibiotics were invented and so was the Antimicrobial Resistance (AMR) due to constitutional resistance makeup carried by the bacteria themselves.
Penicillin, the first antibiotic which saved countless lives and heralded a new era in healthcare, was discovered by an accident which earned Dr. Alexander Fleming the Nobel Prize in 1945.
Scientists working with clinical and environmental samples in their laboratories are not directly exposed to the real scenario of MDR in the hospitals and communities.
Department of Human Health and Diseases, Indian Institute of Advanced Research, Koba Institutional Area, Gandhinagar 382 007, Gujarat, India
Dr. Ashima Kushwaha Bhardwaj has been working at the Indian Institute of Advanced Research (IIAR), Gandhinagar, Gujarat, India, since 2006. At IIAR, she directs the Department of Human Health and Diseases with a major focus on the molecular epidemiology of antibiotic resistance. Dr. Bhardwaj’s current research is centered around unraveling the mechanisms of spread of antibiotic resistance amongst clinical isolates of microbes causing major diarrheal diseases in South East Asian peninsular regions. As an Associate Professor, she also teaches undergraduate and graduate courses at the University of IAR, Gandhinagar. She has directed several post-graduate and Ph.D scholars’ theses at IIAR. Her research has been published in leading peer-reviewed journals and has been internationally acclaimed.