We reproduced mouse model of bronchial asthma, evaluated metabolic shifts of serum homeostasis during disease development, and compared these results with the data on metabolic shifts in bronchial asthma patients.
Nowadays it is quite clear that diagnosis and correction of athletes’ functional state should be made with taking into account the results of the integral study methods and with use of individually selected training conditions.
The comparative analysis of the results of sanogenetic monitoring of the health of adolescents from various regions of the Russian Federation (Moscow, Moscow and Novgorod oblasts, and the Republic of Adygea) has demonstrated disturbances of the state of the cardiac muscle, vascular tone, and the systems of autonomic control of heart rate and peripheral blood pressure in schoolchildren in Moscow.
Russia started the process of the gradual transfer of the education system to the new standards. These new educational standards reflect the social order and are seen as a social compact matching the requirements imposed by the family.
Arterial hypertension is one of the most widespread noninfectious diseases. It often first manifests itself in adolescence, and statistical data indicate that, during the past 10 years, the incidence of cardiovascular pathology has doubled in children 14 years of age and increased 2.5 times in adolescents, which is probably a result of the improved diagnosing of cardiac diseases in childhood.
Contemporary theories of sanogenetic adaptation, epigenetic management and constitutionality of biological regulation systems are discussed. An organism has special sanogenetic systems designed to analyze the changing internal and external conditions and to ensure the most effi cient mode of interaction.
Based on reference and our obtained data, the analysis of the element status (hair, blood) taken from aborigines of the North was carried out. It was found that ecological and genetic factors infl uence the mineral metabolism in the northern populations.
Modern sport imposes high requirements on human body and puts forward the problems of studying functional status of various systems of the body and instant level of physical performance and timely diagnosis of prepathological and pathological conditions arising from inappropriate organization of the training process.
Health hazard from natural and anthropogenic sources has begun to be analyzed years ago. Until recently this analysis was primarily applied for human safety in incidents. However, due to stochastic features of risk assessment its applicability to the diagnosis, prevention, and protective or compensatory measures in some cases can be very limited.
Here we discuss the correlation of idiopathic scoliosis development with the degree and directionality of metabolic shifts in children. Comparative analysis included the data obtained during examination of children with idiopathic scoliosis and kyphosis and pupils of Moscow general education schools.
The paper presents description of the concept and practical applications of modern diagnostic methods in monitoring of health and environmental safety of population in megalopolises. The main methods used are multielement analysis and laser correlation spectroscopy of biological samples.
Moscow Institute of Open Education, Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow
Mikhail Karganov was born 13.11.1956 in Odessa, USSR. In 1980 he was graduated from Moscow Mendeleev Institute of Chemical Technology, organic-fuel faculty, technology of microbiological production. At the age of 28, he presented his Ph.D Theses “Study of the role of peptides in the regulation of muscle tone in vestibulopathy” at the Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences. In 2001, he accomplished his postdoctoral studies “Peptidergic mechanisms of occurrence and elimination of experimental neuropathologic syndromes” at the same institute and was given Dr. Sci. degree. From 1980 till 1988 – assistant researcher, from 1988 till 2000 – senior researcher at the Institute of General Pathology and Pathophysiology, since 2001 - head of Laboratory of Polysystemic Investigations of Institute of General Pathology and Pathophysiology. M. Karganov has published more than 100 papers in reputed journals and works as an editorial board member. Since 2006, works as a professor. The sphere of his scientifi c researches over the last 15 years includes the development of new biophysical methodologies that enable rapid detection in a noninvasive mode of the functional status of regulatory systems responsible for preservation of its adaptive potencies of the body.
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