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Plant Metabolites in Treatment of Cancer and Cerebrovascular Diseases

Plant Metabolites in Treatment of Cancer and Cerebrovascular Diseases

Plant Metabolites in Treatment of Cancer and Cerebrovascular Diseases

  • Editor: Manikant Tripathi   Manzoor Ahmad Mir  
  • ISBN: 978-1-63278-073-7
  • DOI: 10.4172/978-1-63278-073-7
  • No of Pages: 63
  • Publisher: OMICS International
  • Published On: July 2019 , Tue 30
  • Chapter 1      
    Medicinal Plants in Cancer Treatment and Prevention
    Authors: Umar Mehraj , Bashir Ahmad Sheikh , Syed Suhail Hamdani , Manzoor Ahmad Mir

    Cancer is a major health problem and remains one of the leading causes of mortality and morbidity in the world. It is the second leading cause of death, after the cerebrovascular disease among the non-communicable disease. Cancer results from damage to genes encoding proteins that regulate the cell division cycle. The cancer cells are characterized by two distinct properties i.e., they divide indefinitely and they colonize other tissues and organs of the body.

  • Chapter 2      
    Natural Herbs in Cerebrovascular diseases
    Authors: Umar Mehraj , Bashir Ahmad Sheikh , Syed Suhail Hamdani , Manzoor Ahmad Mir

    Neurological disorders and neurodegenerative disorders pose a significant threat in the modern-day arena. Cerebrovascular diseases are the leading cause of mortality and morbidity worldwide. These diseases pose many clinical challenges and even experienced clinicians can arrive at the point where work- up, treatment, or prognostic thinking falters. Cerebral ischemia is the third cause of death and leading cause of chronic disability across the globe. Cerebral ischemia is one of the foremost types of stroke prevalent in the human population and may develop due to rapid hypoxia–hypoglycemia (embolism, thrombosis, systemic hyporeperfusion and venous thrombosis). Stroke has become one of the foremost causes of stern, long-term functional disability, neurologic impairment and is the cause of mortality worldwide. Depending on the rigorousness and category, stroke can leave an individual with a residual impairment of psychological, physical, social and cognitive functions. However, presently there are no recognized drug therapies to improve recovery after stroke. The established risk factors, of cerebral ischemia include hyperlipidemia/dyslipidemia, diabetes, hypertension, smoking; microvascular rupture, age and observed comorbidity, such as HIV infection, sickle cell anemia disease and cerebral malaria are increasingly being encountered in the tropics.

  • Chapter 3      
    Natural Herbs for Cerebral Ischemia
    Authors: Umar Mehraj , Bashir Ahmad Sheikh , Syed Suhail Hamdani , Manzoor Ahmad Mir

    Cerebral ischemia or cerebrovascular ischemia or brain ischemia, is a condition that occurs when there isn’t enough blood flow to the brain to meet metabolic demand. This leads to limited oxygen supply or cerebral hypoxia and leads to the death of brain tissue, cerebral infarction, or ischemic stroke. Cerebral ischemia is the third cause of death and leading cause of chronic disability across the globe. Cerebral ischemia is one of the foremost types of stroke prevalent in the human population and may develop due to rapid hypoxia–hypoglycemia (embolism, thrombosis, systemic hyporeperfusion and venous thrombosis). It is characterized by blood flow disruption to the brain with rapid depletion of glucose and cellular energy, thereby resulting in ionic imbalances which in turn initiate a series of damaging events. Stroke has become one of the foremost causes of stern, longterm functional disability, neurologic impairment and is the cause of mortality worldwide. Depending on the rigorousness and category, stroke can leave an individual with enduring damage of psychological, physical, social and cognitive functions. However, presently there are no recognized drug therapies to improve recovery after stroke. The established risk factors, of cerebral ischemia include hyperlipidemia/dyslipidemia, diabetes, hypertension, smoking; micro-vascular rupture, age and observed comorbidity, such as HIV infection, sickle cell anemia disease and cerebral malaria are increasingly being encountered in the tropics

  • Manikant Tripathi

    Centre of Excellence, Department of Microbiology.

    .ecause of improper treated or untreated solid and liquid wastes discharged from tanneries

  • Manzoor Ahmad Mir

    Senior Assistant Professor, Department of Bioresources

    Dr. Manzoor Ahmad Mir holds Master’s Degree in Zoology from HNBG Central University after qualifying prestigious National level CSIR-JRF-NET examination and worked jointly for his Ph. D at Jawaharlal Nehru University New Delhi and CSIR-Institute of Microbial Technology Chandigarh in the field of Immunology and Cell Biology. He currently teaches Endocrinology, Animal Physiology, Immunology and Developmental Biology at the Department of Bioresources, University of Kashmir, and has been a Research Scientist at SATCAS Stroke Research Chair Majmaah University KSA. Dr Manzoor has research and has attended many courses and conferences on immunology, cancer Biology, stroke biology and endocrinology at USA, UK, Kuwait, China, UAE and Saudi Arabia.

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