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Journal of Leukemia is a peer reviewed medical journal that includes a wide range of fields in Leukemia, Multiple Myeloma, Acute Lymphoblastic Leukemia, Acute Myleoid Leukemia, Chronic Lymphocytic Leukemia, Chronic Myleloid Leukemia, Hairy Cell Leukemia, Pediatric Leukemia, Leukemia drugs, Stem Cell Transplant, Plasma cell Leukemia, Mast cell Leukemia, Lymphoma Cancer, Lymphoma Symptoms, Spleen cancer, Acute Myelomonocytic Leukemia, Aleukemic Leukemia , Lymphosarcoma, Megakaryocytic Leukemia, Feline Leukemia complex, Epidemiologic studies and other Hematologic malignancies and creates a platform for the authors to make their contribution towards the journal and the editorial office promises peer process for the submitted manuscripts to ensure quality.
Leukemia is one of the best open access journals that aims to publish the most complete and reliable source of information on discoveries and current developments in the mode of Original articles, Review articles, Case reports, Short communications, etc. in the field and provides free online access to the researchers worldwide.
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Leukemia is a cancer of the blood cells. Leukemia begins in a cell in the bone marrow. The cell undergoes a change and becomes a type of leukemia cell. Once the marrow cell undergoes a leukemic change, the leukemia cells may grow and survive better than normal cells. Over time, the leukemia cells crowd out or suppress the development of normal cells. The rate at which leukemia progresses and how the cells replace the normal blood and marrow cells are different with each type of leukemia.
It is the most common type of blood cancer and affects 10 times as many adults as children. Most people diagnosed with leukemia are over 50 years old.
Acute lymphocytic leukemia (ALL), also called acute lymphoblastic leukemia, is a cancer that starts from the early version of white blood cells called lymphocytes in the bone marrow (the soft inner part of the bones, where new blood cells are made). The term “acute” means that the leukemia can progress quickly, and if not treated, would probably be fatal within a few months. Lymphocytic means it develops from early (immature) forms of lymphocytes, a type of white blood cell. Acute leukemia requires aggressive, timely treatment.
Chronic lymphocytic leukemia (CLL) is a type of cancer that starts from cells that become certain white blood cells(called lymphocytes) in the bone marrow. The cancer (leukemia) cells start in the bone marrow but then go into the blood.In CLL, the leukemia cells often build up slowly over time, and many people don't have any symptoms for at least a few years. In time, the cells can spread to other parts of the body, including the lymph nodes, liver, and spleen.
Chronic Lymphocytic Leukemia (CLL) is a slow-growing cancer of lymphoid cells that usually affects people over 55 years of age. It is estimated to affect about 16,000 people in the U.S. every year. It almost never occurs in children or adolescents.
Chronic myeloid leukemia (CML), also known as chronic myelogenous leukemia, is a type of cancer that starts in certain blood-forming cells of the bone marrow. In CML, a genetic change takes place in an early (immature) version of myeloid cells - the cells that make red blood cells, platelets, and most types of white blood cells (except lymphocytes). This change forms an abnormal gene called BCR-ABL, which turns the cell into a CML cell. The leukemia cells grow and divide, building up in the bone marrow and spilling over into the blood. In time, the cells can also settle in other parts of the body, including the spleen. CML is a fairly slow growing leukemia, but it can also change into a fast-growing acute leukemia that is hard to treat.
Pediatric Leukemia is also called as Juvenile Leukemia and childhood leukemia. Accounts for less than 1% of childhood leukemias Approx. 25-50 children are diagnosed each year in the US Children are usually diagnosed before 2 years old More common in boys than girls Symptoms can take months to develop Usually no symptoms are seen in the early stages Once diagnosed progressive deterioration occurs.
This Leukemia is the most commonly diagnosed cancer in children, accounting for about 30% of all cases. Approximately 1 in 2,000 children will develop it before the age of 15 years.
Leukemia is not a single disease. Instead, the term leukemia refers to a number of related cancers that start in the blood-forming cells of the bone marrow.Chemotherapy is the major form of treatment for leukemia. This drug treatment uses chemicals to kill leukemia cells. Biological therapy works by using treatments that help your immune system recognize and attack leukemia cells.Targeted therapy uses drugs that attack specific vulnerabilities within your cancer cells. Radiation therapy uses X-rays or other high-energy beams to damage leukemia cells and stop their growth.
Chemotherapy is the standard treatment for many types of leukemia. Even when a cure isn't possible, chemotherapy may help you live longer and feel better.
Plasma cell leukemia (PCL) is a rare and aggressive plasma cell dyscrasia. Patients with PCL have a very poor prognosis with median survival measured in months. PCL can present de novo or following a prodrome of plasma cell myeloma. Patients with PCL tend to present with aggressive clinical features, such as extramedullary disease, bone marrow failure. The treatment of PCL has primarily been palliative, with only a small minority of patients achieving a durable remission.
Mast cell leukemia (MCL) is a very rare form of aggressive systemic mastocytosis accounting for < 1% of all mastocytosis. It may appear de novo or secondary to previous mastocytosis and shares more clinicopathologic aspects with systemic mastocytosis than with acute myeloid leukemia. Symptoms of mast cell activation-involvement of the liver, spleen, peritoneum, bones, and marrow-are frequent.The common phenotypic features of pathologic mast cells encountered in most forms of mastocytosis are unreliable in MCL.
The most common symptom of lymphoma is a painless swelling in a lymph node, usually in the armpit, groin or neck. This is caused by the damaged lymphocytes collecting in that node. The swelling may also ache. Fever, Chills, Unexplained weight loss, These symptoms are nonspecific. This means that they could be caused by any number of conditions unrelated to cancer. For instance, they could be signs of the flu or other viral infection, but in those cases, they would not last very long. In lymphoma, the symptoms persist over time and cannot be explained by an infection or another disease.
The spleen is an organ located under the ribs on the left side of the body. It is part of the lymphatic system, which is composed of lymph nodes, lymph vessels, lymphatic fluid, the tonsils, thymus, spleen, and lymphoid tissue of the digestive tract. Most splenic cancers do not start in the spleen, and those that do are almost always lymphomas. Lymphoma is a type of blood cancer that develops in the lymphatic system. It is more common for a lymphoma to start in another part of the lymphatic system and invade the spleen than it is for lymphoma to start in the spleen itself. There are a number of different types of spleen cancers including lymphoma, non-Hodgkin's lymphoma and some types of T-cell lymphomas. Roughly 70,000 new cases of lymphoma are diagnosed each year in the US.
Acute Myelomonocytic Leukemia one of the more common types of acute myelogenous leukemia, characterized by both malignant monocytes and myeloblasts; it usually affects middle aged to older adults, although it affects people of all ages. AML sometimes is caused by chemotherapy or radiation therapy given to treat another cancer.
In AML, immature leukemia cells rapidly accumulate in the bone marrow, destroying and replacing cells that produce normal blood cells. The leukemia cells are released into the bloodstream and are transported to other organs, where they continue to grow and divide. They can form small masses (chloromas) in or just under the skin or gums or in the eyes. There are several subtypes of AML, which are identified based on characteristics of the leukemia cells.
Leukemia is a serious disease, a cancer of blood or bone marrow. It is a cancer of white blood cells (WBCs). Abnormal production of leukocytes or white blood cells in the bone marrow leads to leukemia, resulting in several health complications. Aleukemic Leukemia is a leukemia in which the leukocyte count is normal or below normal.
In aleukemic leukemia, increased number of white blood cells is not detected in a blood test. It is a rare type of leukemia. This type of leukemia can also be lymphocytic, monocytic, or myelogenous. It can be seen in patients diagnosed with acute/chronic lymphocytic/meylogenous leukemia and also in prolymphocytic leukemia, and myelodysplastic syndrome.
Acute megakaryocytic leukemia (AMeL) is a rare form of acute myeloid leukemia (AML). Even if it is a well-known entity, it could be frequently misdiagnosed as acute myelosclerosis. The disease is rare and, due to difficulty in diagnosis, its exact incidence is not known. Reasonably, it may account for approximately 1-2% of all de novo acute myeloid leukemias (AML) in the adult population, but the incidence in the pediatric age group is higher, partly due to an association with Down syndrome. The incidence of this form of AML shows a high variability according to the different reports, that it ranges from 8 to 15% of all acute leukemias. Clinical experience with this rare leukemia remains limited.
Feline leukemia is a cancerous disease caused by feline leukemia virus (FeLV). Feline leukemia is a disease that only affects cats -- it cannot be transmitted to people, dogs, or other animals. FeLV is passed from one cat to another through saliva, blood, and to some extent, urine and feces. The virus does not live long outside the cat’s body -- probably just a few hours. FeLV is a type of virus called a retrovirus.
Only about 3% of cats in single-cat households have the virus, but for cats that spend time outdoors, the rate is much higher. Still, the prevalence of FeLV has decreased over the last 25 years because of vaccines and reliable tests.
Lymphosarcoma is a malignant tumor in lymphatic tissue, caused by the growth of abnormal lymphocytes. lymphosarcoma cell leukemia has been used to describe the invasion of blood by other types of lymphoma, including large cell, lymphoblastic, and Burkitt's lymphoma, although these are better designated as the particular lymphoma in leukemic phase. When abnormal cells appear in the blood samples of patients with lymphoma, acute myelogenous leukemia must also always be considered, particularly in patients who have received substantial prior chemotherapy or irradiation.
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Journal of Leukemia is supporting the 5th World Conference on Cancer Therapy during september 28-30, 2015 Atlanta, USA with the theme of Exploring the Possibilities towards cancer treatment.
* 2015 Journal Impact Factor was established by dividing the number of articles published in 2013 and 2014 with the number of times they are cited in 2015 based on Google search and the Scholar Citation Index database. If 'X' is the total number of articles published in 2013 and 2014, and 'Y' is the number of times these articles were cited in indexed journals during 2015 then, impact factor = Y/X