ISSN: 2329-6925

Journal of Vascular Medicine & Surgery
Open Access

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Jun Ren
Jun Ren Jun Ren
Division of Vascular Surgery
School of Medicine and Public Health Madison ï»¿
University of Wisconsin 
WI 53705-2275

Being a young vascular biologist, I was trained in biochemistry, molecular biology and physiology. My major research for past several years has been focused on the molecular and cellular mechanisms underlying vascular diseases and developing effective strategies to treat vascular diseases. Using a combination of molecular, biochemical and genetic approaches, we identified that protein kinase C-delta (PKCδ) is a critical stress mediator in vascular injury. My current research mainly focuses on how PKCδ regulates apoptosis of vascular smooth muscle cells (VSMC) and, on the other hand, mediates chemokine release. How injured VSMCs cross talk with adventitial cells, mediate cells differentiation and recruitment during neointima formation in vitro and in vivo. By collaborating with chemical engineers, I also put my effort to develop potent therapy against intimal hyperplasia.

Research Interest

Pathogenesis of restenosis
Chemokines involved intimal hyperplasia
Cross talk between VSMCs and adventitial cells
Endothelial progenitor cells
Gene therapy against intimal hyperplasia


Global Speakers in the subject

Global Experts in the subject


Secondary Common Bile Duct Stones in Congenital Right Side Diaphragmatic Hernia: A Case Report

Kai Huan Yu, Yong Song, Peng Ma, Jia Yu, Ai Min Zhang, Jun Ren and Chen Chen

Case Report: Pancreat Disord Ther 2016, 6: 178
doi: 10.4172/2165-7092.1000178
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